From single DNA sequences to massively parallel sequencing
After over 20 years of conventional Sanger sequencing, next-generation sequencing (NGS) emerged in 2004. With this high-throughput technology, the efficiency of sequencing increased with a significant leap. Rather than merely sequencing single DNA sequences, it was now possible to perform parallel sequencing of many short DNA fragments so that e.g. the whole human genome could be sequenced in less than a week at a fraction of the cost.